Anti-Pigmentation / Skin Conditioning / Anti-inflammatory

Tranexamic Acid

ALSO KNOWN AS: TXA 1,2

A skin-brightening ingredient that fades dark spots, evens out skin tone, and reduces redness. It also helps the skin hold onto moisture for a smoother, more balanced complexion. 1,2

EFFECTIVE CONCENTRATION 2-5% 2

TIME TO RESULTS 8 weeks 2

CATEGORY Anti-Pigmentation 1

STABILITY

Stable · Water-soluble · Avoid direct sunlight and heat 4,5

HOW IT WORKS

UV exposure and inflammation trigger your skin to overproduce melanin, causing dark spots. Tranexamic acid blocks these triggers before excess pigment can form. It also calms inflammation and reduces redness, making it effective for both uneven skin tone and rosacea-prone skin. 2,3

KEY BENEFITS

Reduces Dark Spots and Melasma: Suppresses melanin production at its source for visibly brighter, more even-toned skin. 2
Calms Redness and Rosacea: Reduces visible redness and the appearance of blood vessels through its calming properties. 2
Treats Post-Acne Marks: Reduces both dark marks and red marks left after acne breakouts. 2
Well Tolerated: Minimal side effects compared to traditional depigmenting agents like hydroquinone. 2

INTERACTION WARNINGS

Generally well tolerated by all skin types. May cause mild dryness or irritation initially; introduce gradually. 1,2 As a general reminder, avoid combining Cellexia products with retinol. A patch test is recommended before first use.

FOUND IN

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Reduces Acne and Post-Acne Marks: In an 8-week study, topical tranexamic acid significantly reduced inflammatory acne and helped fade both dark marks and red marks left after breakouts faster than the untreated side. 7
Improves Rosacea-Related Redness: In a study of 20 women with rosacea, topical tranexamic acid improved all patients, with many visible blood vessels disappearing after treatment and results lasting over four months. 8
Topical Matches Oral Results for Melasma: A 12-week clinical trial found that topical 5% tranexamic acid produced melasma improvements comparable to oral tranexamic acid, with no systemic side effects. 9
Meta-Analysis Confirms Efficacy Across 22 Studies: A review of 22 controlled trials confirmed that tranexamic acid significantly reduces melasma severity regardless of how it is administered. 10