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Anti-Aging Anti-wrinkle agent

Matrixyl 3000

Pal-GHK & Pal-GQPR 1

Activates the skin's natural repair process to smooth wrinkles, improve elasticity and tone, and slow visible signs of aging. It targets both sun-related and age-related skin decline. 1,2

EFFECTIVE CONCENTRATION 3% 1
TIME TO RESULTS 4-8 weeks 1,3
CATEGORY Anti-Wrinkle 2
STABILITY

Stable · Avoid direct sunlight and heat 4

HOW IT WORKS

Matrixyl® 3000 combines two peptides that act as messengers, signalling skin cells to repair and renew. The first boosts collagen and hyaluronic acid production for firmer, smoother skin. The second reduces the inflammation triggered by UV exposure and daily stress that accelerates collagen breakdown. Together they address both the cause and visible signs of aging. 1,5

KEY BENEFITS

  • Boosts Collagen and Skin Repair: Stimulates collagen, fibronectin, and hyaluronic acid production to rebuild and strengthen the skin's structure. 1,5
  • Smooths Wrinkles: Reduces wrinkle depth, volume, and density for visibly smoother skin. 1,5
  • Firms and Tones Skin: Improves elasticity and reinforces the proteins that keep skin layers firm and connected. 1,5
  • Slows Visible Aging: Analysis confirmed regular use slowed the skin's measurable aging process by up to 5.5 years. 1

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INTERACTION WARNINGS

Assessed as safe in cosmetics with no adverse reactions in clinical studies. 9 As a general reminder, avoid combining Cellexia products with retinol. A patch test is recommended before first use.

  • Clinically Proven to Reduce Wrinkles: In a clinical study on women applying Matrixyl® 3000 twice daily for two months, deep wrinkle surface area, density, and depth all showed significant reduction, with visible improvement in skin tone. 1
  • Slows the Skin's Aging Process: Analysis confirmed that regular use slowed the skin's measurable aging process by up to 5.5 years. 1
  • Stimulates Collagen and Hyaluronic Acid: Testing confirmed Matrixyl® 3000 significantly increases collagen and hyaluronic acid production in skin cells while reducing key markers of cellular aging. 1
  • Multi-Peptide Serum Reduces Wrinkles in 28 Days: A 28-day study using a serum containing Matrixyl® 3000 showed meaningful reductions in wrinkle number, length, and volume, with a significant firming effect and no adverse reactions reported. 3
  • Long-Term Use Confirms Wrinkle Reduction and Skin Rebuilding: In a 12-month study on 60 photoaged volunteers, a peptide-containing serum produced clinical wrinkle improvement in 70% of subjects, with skin biopsies confirming structural rebuilding in the deeper layers of the skin. 12
  • Palmitoyl Tripeptide Protects Collagen and Increases Skin Thickness: The key peptide in Matrixyl® 3000 was shown to significantly protect collagen from UV damage, and a clinical study confirmed increased skin thickness after four weeks of use. 13
  • Palmitoyl Peptide Blend Rebuilds Skin Structure and Boosts Key Proteins: A study on women applying a blend of palmitoyl oligopeptide and palmitoyl tetrapeptide-7 for two months confirmed significant increases in multiple types of collagen, fibronectin, and hyaluronic acid in skin cells. 14

REFERENCES

  1. https://www.scribd.com/document/820501278/SEDERMA-POS-Matrixyl3000-EN-6
  2. https://www.specialchem.com/cosmetics/product/croda-matrixyl-3000
  3. https://pubmed.ncbi.nlm.nih.gov/37335808
  4. https://sophixnatural.com/wp-content/uploads/2025/06/MSDS-Matrixyl%C2%AE-3000.pdf
  5. https://www.mdpi.com/2079-9284/4/2/16
  6. https://cellexialabs.com/products/jawline-contour-tightening-cream
  7. https://cellexialabs.com/products/neck-tightening-cream
  8. https://cellexialabs.com/products/deep-wrinkle-filler-gel
  9. https://cellexialabs.com/products/body-wrinkle-cream
  10. https://cellexialabs.com/products/eye-lifting-serum
  11. https://cellexialabs.com/products/advanced-glow-reset-serum
  12. https://academic.oup.com/bjd/article-abstract/161/2/419/6642476
  13. https://onlinelibrary.wiley.com/doi/epdf/10.1046/j.1467-2494.2000.00010.x
  14. https://pubmed.ncbi.nlm.nih.gov/25817264/
Professional-Grade Precision for Visible Results
Professional-Grade Precision for Visible Results
Professional-Grade Precision for Visible Results
Professional-Grade Precision for Visible Results
Professional-Grade Precision for Visible Results
Professional-Grade Precision for Visible Results

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