Elasticity improvement / Anti-wrinkle / Anti-aging Agent / Cellular renewal

Argireline

ALSO KNOWN AS: Acetyl Hexapeptide-8 1,2

Visibly reduces the depth of expression lines and wrinkles, particularly on the forehead and around the eyes, by gently relaxing the facial muscles responsible for their formation. 2,3

EFFECTIVE CONCENTRATION 10% 4

TIME TO RESULTS 4 weeks 3

CATEGORY Anti-Wrinkle 1,2

STABILITY

Generally stable · Avoid extreme heat 5,6

HOW IT WORKS

Argireline® mimics a natural protein in the skin that controls how muscles receive signals to contract. By interrupting this process, it reduces the repetitive muscle movements that cause expression lines, keeping skin smoother and more relaxed over time. 2,3,7

KEY BENEFITS

Reduces Expression Lines: Visibly reduces the depth of existing wrinkles caused by repeated facial movements, with significant improvement shown in a study of 60 subjects over 4 weeks. 3
Helps Prevent New Fine Lines: Helps limit the formation of new lines by reducing repetitive muscle contractions over time. 2,3
Smoother Skin Surface: Improves overall skin texture and smoothness, with measurable reductions in skin roughness. 3,4
Needle-Free Alternative: A gentle, non-invasive option compared to more aggressive anti-wrinkle treatments, with a strong safety profile. 2,3

INTERACTION WARNINGS

Altheostem is generally well tolerated and compatible with common actives like hyaluronic acid, niacinamide, and vitamin C. As a general reminder, avoid combining Cellexia products with retinol. Those with sensitive skin should patch test before use, especially when combining with high-strength acids. ¹

FOUND IN

Cremă de contur facial pentru linia maxilarului

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Significant Anti-Wrinkle Efficacy of Argireline® in Clinical Study: A study of 60 subjects tested Argireline® against a placebo for treating wrinkles around the eye area over 4 weeks of twice-daily use. The Argireline® group showed significant improvement in wrinkle appearance and a meaningful decrease in skin roughness compared to placebo. 3
In Vivo Wrinkle Depth and Width Reduction Over 30 Days: In a 30-day study on 20 women, Argireline® applied twice daily reduced wrinkle depth and width across both dry and oily skin types, with skin hydration also improving progressively throughout the study. 11
Argireline® Works Through a Second Anti-Wrinkle Pathway: Computer simulations revealed that Argireline® works through a second mechanism beyond its known anti-wrinkle pathway. By locking a key protein involved in muscle signalling into an inactive state, it prevents the signal that tells facial muscles to contract from being sent, giving it a broader and more reliable wrinkle-reducing effect. 12